Ljungan virus (LV), which belongs to the Parechovirus genus in the Picornaviridae family, was first isolated from bank voles (Myodes glareolus) in Sweden in 1998 and proposed as a zoonotic agent.To improve knowledge of the host association and geographical distribution of LV, tissues from 1685 animals belonging to multiple rodent and insectivore species from 12 European countries were …
Ljungan virus was isolated in 1999 (Niklasson et al. 1999), and has subsequently been detected in many species of small rodents, especially voles (Arvicolinae; Johansson et al. 2003; Hauffe et al. 2010; Salisbury et al. 2013).
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This method is therefore rarely successful for diagnosing Ljungan virus infection. - The Ljungan virus’ so called “2A gene” is doubled, which means that its gene pool is organised in a way that separates it from most other known picorna viruses. Relationship Between Ljungan Virus Antibodies, HLA-DQ8, and Insulin Autoantibodies in Newly Diagnosed Type 1 Diabetes Children. Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift Genomic Organization and Capsid Architecture of Ljungan Virus : a Novel Member of the Picornaviridae Johansson, Susanne (author) Högskolan i Kalmar,Naturvetenskapliga institutionen Lindberg, Michael (thesis advisor) Högskolan i Kalmar,Naturvetenskapliga institutionen Everitt, Einar (thesis advisor) show more Hovi, Tapani, Professor (opponent) 2009-04-21 · This video is unavailable. Watch Queue Queue. Watch Queue Queue Ljungan virus a novel pathogen : Effects on the pregnant female and her offspring Phylogenetic analysis of Ljungan virus and A-2 plaque virus, new members of the Picornaviridae. lnu.se Publications.
sprids av skogssork. - pärluggla äter skogssorkar (huvudpredator). *kan tillämpas på andra patogener med skogssork som värd, t ex Ljungan-virus
2003; Hauffe et al. 2010; Salisbury et al.
Ljungan virus Download PDF Info Publication number US20110300149A1. US20110300149A1 US13/141,758 US200913141758A US2011300149A1 US 20110300149 A1 US20110300149 A1 US
2003; Hauffe et al. 2010; Salisbury et al. 2013). A pathogenic virus of the viral family which includes polio and hepatitis A was isolated from a bank vole near the Ljungan river in the mid-1990s, and named Ljungan virus. Some towns near or by the river are: Matfors; Njurunda; Ånge; References Ljungan virus is a recently identified member of the family Picornaviridae that was isolated from bank voles in Sweden. It has been shown to cause type 1 diabetes-like symptoms and myocarditis in bank voles (Myodes glareolus), and it has been suggested that it has zoonotic potential.
Utbrott av sjukdomssymptom ser ut att utlösas av höga stressnivåer, i alla fall bland gnagare.
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Men svenska virusjägare är detta virus på spåren, och via media har vi fått rapporter om deras framsteg. Nu senast i SVT. In four of these Ljungan virus was found in the stillborn children as well. A control group of twenty women with normal pregnancies showed that each of their placentas was free from the virus. In a corresponding follow up study the scientists found Ljungan virus in the placenta and/or children of all of the five cases examined.
Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift
Phylogenetic analysis of Ljungan virus and A-2 plaque virus, new members of the Picornaviridae. lnu.se Publications.
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Ljungan virus has been detected/isolated in several European countries, the USA, and Japan [10,15,16,17,18,19]. Genetic analyses of the virus strains showed that LVs can be divided into four genotypes [16,17,20]. LVs isolated in Sweden belong to genotypes 1 and 2, while North American strains are classified as genotypes 3 and 4 [16,20].
Ljungan virus (LV) has recently been associated with perinatal death in its natural rodent reservoir and also with developmental disorders of reproduction in laboratory mice. A strong epidemiological association has been found between small rodent abundance in Sweden and the incidence of intrauterine fetal death (IUFD) in humans. 2020-04-23 A pathogenic virusof the viral family which includes polioand hepatitis Awas isolated from a bank volenear the Ljungan river in the mid-1990s, and named Ljungan virus. … 2009-12-01 In April 2003, the (nearly) complete genome sequence of an American Ljungan virus was reported (Johansson et al., 2003; AF538689). In 2016 a fifth type of Ljungan virus was found in gulls (Larus sp.) in Japan (Mitake et al., 2016). Search for Ljungan virus sequences on GenBank Ljungan virus (LV) is a suspected human pathogen recently isolated from bank voles (Clethrionomys glareolus). In the present study, it is revealed through comparative sequence analysis that three newly determined Swedish LV genomes are closely related and possess a deviant picornavirus-like organization: 5' untranslated region-VP0-VP3-VP1-2A1-2A2-2B-2C-3A-3B-3C-3D-3' untranslated region.
Humant parechovirus är det virus som genetiskt är mest likt Ljunganvirus och Avhandlingen heter ”Ljungan Virus Replication in Cell Culture”.
Samsoe A, Papadogiannakis N, Hultman T, Sjöholm A, Klitz W, Niklasson B. Ljungan virus present in intrauterine fetal death diagnosed by both immunohisto-chemistry and PCR. Birth Defects Ljunganvirus drabbar sorkar och andra gnagare. Det tillhör gruppen parechovirus, vars humana varianter drabbar oss alla någon gång under livet, i regel utan att ge allvarligare symtom. Nio av tio barn får någon human parechoinfektion under de två första åren i livet, sannolikt oftast asymtomatiskt. Ljungan Virus Replication in Cell Culture Jens-Ola Ekström School of Pure and Applied Natural Sciences University of Kalmar, Sweden, 2007 Akademisk avhandling som, för vinnande av doktorsexamen i biomedicinsk vetenskap vid Fakulteten för naturvetenskap och teknik vid Högskolan i Kalmar, Epidemiologic and experimental data support the notion that Ljungan virus (LV), endemic in some rodent populations in Sweden, Denmark, and the United States, can cause morbidity and mortality in animals and humans. LV infection can cause type I diabetes mellitus, myocarditis, and encephalitis in ban … Ljungan virus types 1 to 6 belong to the species Parechovirus B, genus Parechovirus..
Det är fortfarande … The Ljungan virus is difficult to grow in a laboratory cell cultures. This method is therefore rarely successful for diagnosing Ljungan virus infection. - The Ljungan virus’ so called “2A gene” is doubled, which means that its gene pool is organised in a way that … Blixt M, Niklasson B, Sandler S (2007) Characterization of beta-cell function of pancreatic islets isolated from bank voles developing glucose intolerance/diabetes: an animal model showing features of both type 1 and type 2 diabetes mellitus, and a possible role of the Ljungan virus.